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The Pros and Cons of Testosterone Therapy

Which Form of Testosterone Is Most Effective? TRT Injection
TRT can cause fluctuations in testosterone levels, which can affect energy levels, libido, mood, and the presence of symptoms such as breast tenderness. The U.S. Food and Drug Administration (FDA) approves testosterone replacement therapy for males who have low testosterone levels due to a known medical condition (hypogonadism). If you have an abnormally low T, boosting your testosterone levels with TRT can help bring your energy levels back to normal. The tests are usually repeated at least twice to confirm low levels [38].
For example, two people could have the same testosterone level on a blood test, but one person might feel great while the other feels terrible. That’s why doctors consider both your test results and how to maintain fertility on trt you feel when deciding whether to adjust your dosage. It’s important for men on TRT to regularly see their doctor to have their testosterone levels checked. Age and weight are not static; they change over time, which means TRT dosage may also need to change. A study of over 6,300 patients showed that TRT had a mild protective effect on the heart, reducing the risk of heart attacks. However, it’s important to approach this benefit with caution.
The usual starting dose is 6 pumps daily (about the size of 2 quarters) applied to the thighs. It typically takes about 3 to 6 weeks for noticeable improvements after a dosage adjustment. However, it can take up to 6 months for the full benefits of TRT to be realized. If your dosage is too low, you may continue to experience low testosterone symptoms such as fatigue, low libido, or difficulty concentrating. Blood tests will help determine if an increase in dosage is necessary. On the other hand, people who follow a healthy diet that includes lean proteins, whole grains, fruits, and vegetables may find that they need a different TRT dosage.
TRT is a prescription-only treatment and should be taken under a healthcare provider’s supervision. That is why one of our doctors at Morph Wellness will assess symptoms, perform necessary tests, and monitor progress to ensure safe and effective treatment. There are some important recommendations that those receiving TRT should follow as precautionary measures. One should have baseline bone density testing (DEXA) and regular bone density tests (to rule out osteoepenia or osteoporosis). A primary reason is due to the many side effects of long-term testosterone replacement therapy, including a controversial increased risk of heart disease.
The biggest difference is that the doses of testosterone used in TRT are small, designed to achieve natural levels of the hormone in the blood. The doses used by some athletes are as much as 10 to 100 times higher than those given medically. Also, the steroids are often combined (“stacked”) with other substances like stimulants, pain relievers, and growth hormones to boost the overall muscle-building effect. The blood tests measure total serum testosterone, complete blood count (hematocrit), and prostate-specific antigens (PSA).
To find out that I had chronically low testosterone, that it was basically a chemical problem, that was huge. The way my prescription was set up, my hormone levels would spike and crash really fast. I’d be on cloud nine for a few days then have a week-long unwinding period where I felt like shit again. I’ve always been a “figure it out yourself” kind of guy, so I decided to take matters into my own hands. After one year of TRT, many men report significant improvements in vitality, energy, and mental clarity.
Together, you and your healthcare provider will decide if TRT is right for you. Testosterone replacement therapy (TRT) is an option for men who have low testosterone levels due to male hypogonadism. TRT involves taking manufactured forms of testosterone to regulate your levels of this hormone. Low libido and erectile dysfunction, for example, have many contributing factors to rule out, including heart disease and psychological issues. Your doctor will measure your testosterone levels at the 3- and 6-month marks after treatment begins.
In Canada, responsible TRT providers emphasize personalized care plans and ongoing medical supervision to reduce risk. This approach ensures therapy is adjusted to suit your body—not just your lab results. This change can affect other hormones and systems, such as sperm production and estrogen balance, which is why medical supervision is critical. Testosterone replacement therapy (TRT) is an increasingly common treatment for men dealing with the effects of low testosterone—fatigue, low libido, muscle loss, and mood changes. Testosterone Replacement Therapy (TRT) offers significant benefits for men with low testosterone, including improvements in physical, mental, and sexual health. Long-term commitment is often necessary to sustain TRT’s benefits, as testosterone levels may decline again if therapy is stopped. Healthcare providers use a combination of blood tests and symptom evaluations to determine whether TRT is suitable.